Polyarteritis nodosa in a patient with primary immunodeficiency

Authors

  • Camila Bo Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina
  • Ludmila Rodríguez Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina
  • Carla Chackelevicius Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina
  • Karen Ginzburg Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina
  • Viviana Leiro Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v31i1.2765

Keywords:

cutaneous polyarteritis nodosa, primary immunodeficiency

Abstract

Cutaneous polyarteritis nodosa is a rare type of vasculitis that affects small and medium-sized blood vessels. While sometimes associated with infections, inflammatory diseases, drugs, and malignant neoplasms, no relationship with immunodeficiencies has been found in reviewed literature. The pathophysiology of cutaneous polyarteritis nodosa is not completely understood, however, mediation by immune complexes is suggested. Clinically, it is characterized by the presence of livedo reticularis and erythematous and painful nodules that ulcerate. A case of cutaneous polyarteritis nodosa is presented in a patient with primary immunodeficiency

Author Biographies

  • Camila Bo, Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina

    Second-year attending physician, Dermatology Unit

  • Ludmila Rodríguez , Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina

    Staff Physician, Dermatology Unit

  • Carla Chackelevicius, Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina

    Immunologist, Dermatology Unit

  • Karen Ginzburg, Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina

    Chief Resident, Dermatology Unit

  • Viviana Leiro, Francisco J. Muñiz Hospital, City of Buenos Aires, Argentina

    Head of Service, Dermatology Unit

References

I. Daoud MS, Hutton KP, Gibson LE. Cutaneous periarteritis nodosa: a clínico pathological study of 79 cases. Br J Dermatol. 1997;136:706-713.

II. Nakamura T, Kanazawa N, Ikeda T, et ál. Cutaneous polyarteritis nodosa: revisiting its definition and diagnostic criteria. Arch Dermatol Res. 2009;301:117-121.

III. Morgan AJ, Schwartz RA. Cutaneous polyarteritis nodosa: a comprehensive review. Inter J Dermatol. 2010;49:750-756.

IV. Kawakami T, Yamazaki M, Mizoguchi M, et ál. High titer of anti-phosphatidylserine- prothrombin complex antibodies in patients with cutaneous polyarteritis nodosa. Arthritis Rheum. 2007;57:1507-1513.

V. Luo Y, Alexander M, Gadina M, O'Shea JJ, et ál. JAK-STAT signaling in human disease: From genetic syndromes to clinical inhibition. J Allergy Clin Immunol. 2021;148:911-925.

Downloads

Published

2025-04-04

Issue

Vol. 31 No. 1 (2025): January-April

Section

Clinical Cases

License

Copyright (c) 2025 on behalf of the authors. Reproduction rights: Argentine Society of Dermatology

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

El/los autor/es tranfieren todos los derechos de autor del manuscrito arriba mencionado a Dermatología Argentina en el caso de que el trabajo sea publicado. El/los autor/es declaran que el artículo es original, que no infringe ningún derecho de propiedad intelectual u otros derechos de terceros, que no se encuentra bajo consideración de otra revista y que no ha sido previamente publicado.

 

Le solicitamos haga click aquí para imprimir, firmar y enviar por correo postal la transferencia de los derechos de autor