Paradoxical psoriafisorm reactions due to anti TNF-alpha biologic treatment

Authors

  • Luciana L. Tirelli Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina
  • Paula C. Luna Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina
  • Juan J. Solé Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina
  • Alejandra A. Panizzardi Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina
  • Bruno Ferrari ECHO Group Psoriasis Argentina (Extension for Community Healthcare Outcomes), Autonomous City of Buenos Aires, Argentina
  • Luis D. Mazzuoccolo ECHO Group Psoriasis Argentina (Extension for Community Healthcare Outcomes), Autonomous City of Buenos Aires, Argentina
  • Cristina Echeverria ECHO Group Psoriasis Argentina (Extension for Community Healthcare Outcomes), Autonomous City of Buenos Aires, Argentina
  • María T. Gonzáles Baschiera ECHO Group Psoriasis Argentina (Extension for Community Healthcare Outcomes), Autonomous City of Buenos Aires, Argentina
  • Federico Barrera Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina
  • Andrés Label Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina
  • Marina Mónaco Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina
  • Margarita Larralde Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v26i2.2078

Keywords:

Psoriasis, Paradoxical psoriasiform reactions, Biologic treatment, Anti-TNF-alpha

Abstract

As a consequence of the advance in different medical treatments, like with the use of biologic drugs such as anti-TNF-alpha, there can be seen paradoxical psoriasiform reactions. The paradoxical reactions consist of the exacerbation or the appearance of a new symptom or another disease that, generally, improve with the use of biological agents such as anti-TNF-alpha, drugs have several indications related to the treatment of different inflammatory pathologies, hence, it is crucial that every specialist who prescribes them are aware of this secondary effect.

The aim of this article was to observe and describe the demographic and clinical characteristics of a group of patients with paradoxical psoriasiform reactions; and to compare them with the literature.

Author Biographies

Luciana L. Tirelli, Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina

ECHO Group Psoriasis Argentina (Extension for Community
Healthcare Outcomes)

Paula C. Luna, Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina

ECHO Group Psoriasis Argentina (Extension for Community
Healthcare Outcomes)

Juan J. Solé, Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina

ECHO Group Psoriasis Argentina (Extension for Community
Healthcare Outcomes) 

Alejandra A. Panizzardi, Dermatology Service, German Hospital, Autonomous City of Buenos Aires, Argentina

ECHO Group Psoriasis Argentina (Extension for Community
Healthcare Outcomes) 

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Published

2020-06-25

Issue

Section

Original Articles