Weber-Christian panniculitis

Authors

  • Agustina Alves Magalhaes Dr. Teodoro Álvarez General Acute Hospital, City of Buenos Aires, Argentina
  • Andrea C. Soto Dr. Teodoro Álvarez General Acute Care Hospital, City of Buenos Aires, Argentina
  • María L. Ortellado Dr. Teodoro Álvarez General Acute Hospital, City of Buenos Aires, Argentina
  • María Emilia Villani Dr. Teodoro Álvarez General Acute Care Hospital, City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/da.v31i3.2989

Keywords:

Weber Christian panniculitis, idiopathic, nodules, corticotherapy

Abstract

Weber Christian panniculitis is a chronic, febrile, and recurrent disease characterized by erythematous, occasionally painful subcutaneous nodules, commonly associated with systemic symptoms. Its etiology is idiopathic and its prevalence remains unknown. It’s commonly observed in women between 20 and 60 years old. The key pathological finding is nodular inflammation of the fat lobes in the hypodermis. We present a case of Weber Christian panniculitis in this report.

Author Biographies

Agustina Alves Magalhaes, Dr. Teodoro Álvarez General Acute Hospital, City of Buenos Aires, Argentina

First-year Resident Physician, Dermatology Specialist Program, University of Buenos Aires (UBA)

Andrea C. Soto, Dr. Teodoro Álvarez General Acute Care Hospital, City of Buenos Aires, Argentina

Staff Physician, Dermatology Division

María L. Ortellado, Dr. Teodoro Álvarez General Acute Hospital, City of Buenos Aires, Argentina

Staff Physician, Pathological Anatomy Service

María Emilia Villani, Dr. Teodoro Álvarez General Acute Care Hospital, City of Buenos Aires, Argentina

Head of the Dermatology Division

References

I. Zheng W, Song W, Wu Q, Yin Q, et ál. Analysis of the clinical characteristics of thirteen patients with Weber-Christian panniculitis. Rev Clinical Rheumatology. 2019;38:3635-3641.

II. Castellano-Cuesta JA, Velasco-Pastor M, Alfaro-Rubio A. Eritema nudoso y otras paniculitis. Rev Sociedad Val Reuma. 2009;3(1):17-37.

III. Oliveira A, Rodrigues S, Jorge R, Crespo J. Weber-Christian disease: unknown etiology systemic panniculitis. Acta Med Port. 2010;23:1113-1118.

IV. Miranda-Bautista J, Fernández-Simón A, Pérez-Sánchez P, Menchén L. Weber-Christian disease with ileocolonic involvement successfully treated with infliximab. World J Gastroenterol. 2015;21:5417-5420.

V. Briceño-Moya F, Hurtado-Díaz J, Espinoza-Sánchez ML. Eritema nudoso crónico de localización generalizada: a considerar enfermedad de Weber-Christian. Rev Med Inst Mex Seguro Soc. 2020;58:348-352.

VI. Pongratz G, Ehrenstein B, Hartung W, Schölmerich J, et ál. A patient with Pfeifer-Weber-Christian disease. Successful therapy with cyclosporin. A case report. BMC Musculoskelet Disord. 2010;11:18.

VII. Vivero F, Barrera R, Pui J, Nicomedes A, et ál. Enfermedad de Weber-Christian con compromiso orbitario refractaria a inmunosupresores convencionales y respuesta a adalimumab. Rev Argent Reumatol. 2024;35:72-75.

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Published

2025-12-01

Issue

Vol. 31 No. 3 (2025): September-December

Section

Clinical Cases

License

Copyright (c) 2025 on behalf of the authors. Reproduction rights: Argentine Society of Dermatology

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